The collection primarily consists of interviews conducted by James H. Jones with medical professionals who were responsible for the care of David Vetter. Vetter suffered from severe combined immunodeficiency (SCID) and was popularly known as the "Bubble Boy." The interviews were conducted in 2001 for a book that was ultimately not completed. Additionally, the collection contains audiovisual materials and photographs related to Vetter.
The collection consists of audiovisual recordings related to bioethics, the bulk of which are recordings of lectures delievered at the Kennedy Institute of Ethics (KIE). This includes the KIE's Intensive Bioethics Courses and Advanced Bioethics Courses. The recordings are in a variety of formats, including audio cassettes, compact discs, DVDs, micro cassettes, VHS cassette tapes, 1/4" open reel audio, and other formats.